Outlive: The Science and Art of Longevity

Product Information

Those are the three biggest causes of death — heart disease, cancer, and Alzheimer’s. Now, all of those diseases have different effects and treatment methods, and over the last several decades, we’ve learned a lot about preventing and reversing them. However, there’s one disease that underlies all three of these. It’s the common factor behind all three biggest causes of death — Type 2 diabetes. To function as a healthy, fit 60-year-old when we’re 80 and reach the limits of our health and lifespan, we have to break down “exercise” into its four most important parts, he argues: strength, stability, aerobic efficiency and peak aerobic capacity. I’ll start with what longevity isn’t. Longevity does not mean living forever. Or even to age 120, or 150, which some self-proclaimed experts are now routinely promising to their followers. Barring some major breakthrough that, somehow, someway, reverses two billion years of evolutionary history and frees us from time’s arrow, everyone and everything that is alive today will inevitably die. It’s a one-way street. And fasting for longer periods comes at a price. “You are virtually guaranteed to miss your protein intake with this approach,” he says. “One not uncommon scenario that we see with TR is that a person loses weight on the scale, but their body composition alters for worse: they lose lean mass (muscle) while their body fat stays the same or even increases,” says Attia.

Attia writes: “data comes from studies of… people who have lived to the age of one hundred and beyond, often in good health… many of them get to enjoy one, or two, or even three Bonus Decades…. Researchers… [found that] individuals [had] very little in common with one another genetically… Natural selection has endowed us with genes that work beautifully to help us develop, reproduce, and then raise our offspring [but] after the age of reproduction, natural selection loses much of its force… [Yet] a handful of potential longevity genes… are possibly relevant to our strategy. One [gene]… called … APOE (apolipoprotein E) that is involved in cholesterol transport and processing, and it has three variants: e2, e3, and e4… The e2 variant of APOE… seems to protect its carriers against dementia—and it also turns out to be very highly associated with longevity… FOXO3 belongs to a family of “transcription factors,” which regulate how other genes are expressed—meaning whether they are activated or “silenced.”… When FOXO3 is activated, it in turn activates genes that generally keep our cells healthier. It seems to play an important role in preventing cells from becoming cancerous as well.” Those four main pillars focus on the different areas Dr. Peter wants to maintain good health even into old age. He’s playing the long game and working hard to maintain the strength and overall good health he’ll need to continue living an active and fulfilled life even when he’s over 100 years old. It’s not about exercising more , especially as he gets older. It’s about exercising intentionally. Why you should forget about diets, and focus instead on nutritional biochemistry, using technology and data to personalize your eating pattern. When I ask Attia how much it costs to sign up for treatment at Early Medical, he sounds rather coy. “It varies – it’s not a fixed fee. It’s a little more in the first year and then the cost sort of ratchets down because we’re doing more work early on.”A pause. “Go exercise! How much does it cost to really educate people to exercise? That doesn’t matter how much money you have. Now, I’m not so naive as to think that a single mom who’s working three jobs won’t have less time to exercise. Clearly, there will be gaps in outcomes, but I don’t think those gaps have to be enormous.”

Attia writes: “The metabolic derangement that leads to type 2 diabetes also helps foster and promote heart disease, cancer, and Alzheimer’s disease… all “diets” are similar… protein becomes critically important as we age… Exercise is by far the most potent longevity “drug.” No other intervention does nearly as much to prolong our lifespan and preserve our cognitive and physical function. But most… don’t do nearly enough—and exercising the wrong way can do as much harm as good…” The first thing you need to know about protein is the standard recommendations for consumption are a joke,” says Attia. “Right now the US Recommended Dietary Allowance (RDA) is 0.8/kg of body weight per day. This may reflect how much protein we need to stay alive, but it’s a far cry from what we need to thrive,” he adds.A data- and anecdote-rich invitation to live better, and perhaps a little longer, by making scientifically smart choices. Comments that harass other posters will be deleted. Please be respectful toward other contributors. In real-world terms, he says, that means someone who is breathing poorly while shovelling in their garden, for instance, is putting themselves at increased risk of injury.

Peter Attia takes several supplements, including fish oil (omega-3 fatty acids), Vitamin D3, probiotics, iron, l-theanine, magnesium, zinc, and lithium. What companies does Peter Attia invest in? Machell, Ben (9 June 2023). "How to stay fit over 60? 9 changes to make now". The Times of London . Retrieved 24 August 2023. The Edge is Hone Health’s editorial operation. Hone is an online clinic that helps people optimize their hormones. As part of your subscription and as medically indicated, physicians prescribe medications, and recommend supplements that are delivered to you from the comfort of your home.Attia agrees, with a twist. “Fasting triggers many of the physiological changes and cellular mechanisms that we want to see,” he says. But, he’s not convinced the trade-offs of long-term, severe caloric restriction—like weakened immunity, greater susceptibility to sarcopenia (muscle loss), and constant hunger—are worth it for everyone. Especially people who are already metabolically healthy and eating a high-quality diet. Per Attia, carbs shouldn’t be labeled as “good” or “bad.” It’s more about how your body individually responds to them. Depending on your metabolism, specifically your insulin sensitivity, your tolerance to carbs is likely different from that of your neighbor, friend, or spouse. Outlive: The Science & Art of Longevity - New Book by Peter Attia". Peter Attia . Retrieved 24 March 2023. Attia P. TED: Is the Obesity Crisis Hiding a Bigger Problem?". ted.com. 24 April 2018 . Retrieved 24 August 2023. AI Dubbing Automatically translate and dub new or existing videos in over 100’s of languages with AI video dubbing.